" [HTML] Mitophagy: an emerging role in aging and age-associated diseases G Chen, G Kroemer, O Kepp - Frontiers in cell and developmental …, 2020 - frontiersin.org … However, recent studies have shown that mitophagy has a key function in d…

" Mitophagy in degenerative joint diseases K Sun, X Jing, J Guo, X Yao, F Guo - Autophagy, 2021 - Taylor & Francis … novelty of mitophagy, we provide an overview of mitophagy pathways and discuss the rolesof mitophagy in IVDD and OA. We al…

" Mitophagy and neuroprotection G Lou, K Palikaras, S Lautrup… - Trends in molecular …, 2020 - Elsevier … Conversely, defective mitophagy leads to … mitophagy in these diseases, and underlyingmolecular mechanisms, and highlight novel thera…

" Mitochondrial dysfunction and mitophagy in Parkinson's disease: from mechanism to therapy AB Malpartida, M Williamson, DP Narendra… - Trends in biochemical …, 2021 - Elsevier … of the mechanisms regulating mitophagy and the causes of … m…

" Mitophagy pathways in health and disease SA Killackey, DJ Philpott, SE Girardin - Journal of Cell Biology, 2020 - rupress.org … studies that have changed the way mitophagy is understood, from initiation … mitophagymaintains mitochondrial…

" Defective mitophagy in Alzheimer's disease JA Pradeepkiran, PH Reddy - Ageing research reviews, 2020 - Elsevier … , ubiquitin mediated mitophagy and basal mitophagy. This … or natural mitophagy enhancers,that influence mitophagy in AD. ……

" Molecular mechanisms and physiological functions of mitophagy M Onishi, K Yamano, M Sato, N Matsuda… - The EMBO …, 2021 - embopress.org … Defects in mitophagy are associated with various pathological conditions such as … ofmitophagy, and…

" [HTML] Accumulation of damaged mitochondria in alveolar macrophages with reduced OXPHOS related gene expression in IPF E Tsitoura, E Vasarmidi, E Bibaki… - Respiratory …, 2019 - respiratory-research.biomedcentral … … Mitochondria homeost…

" Redox imbalance in idiopathic pulmonary fibrosis: a role for oxidant cross-talk between NADPH oxidase enzymes and mitochondria C Veith, AW Boots, M Idris, FJ van Schooten… - Antioxidants & redox …, 2019 - liebertpub.com … in various impo…

” Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis M Bueno, J Calyeca, M Rojas, AL Mora - Redox biology, 2020 - Elsevier … Our understanding of the pathobiology underlying IPF is still incomp…

” The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer YA Wen, X Xiong, T Scott, AT Li, C Wang… - Cell Death & …, 2019 - nature.com … mitochondrial metabolism as a key regulator of Wnt sig…

” [HTML] Empagliflozin activates Wnt/β-catenin to stimulate FUNDC1-dependent mitochondrial quality surveillance against type-3 cardiorenal syndrome C Cai, F Wu, B Zhuang, Q Ou, X Peng, N Shi… - Molecular …, 2022 - Elsevier … Mitochondrial …

” Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction J Miao, J Liu, J Niu, Y Zhang, W Shen, C Luo, Y Liu… - Aging cell, 2019 - Wiley Online Library … 2.7 Wnt/β-catenin/RAS axis …

” [HTML] Impaired mitochondrial ATP production downregulates Wnt signaling via ER stress induction R Costa, R Peruzzo, M Bachmann, G Dalla Monta… - Cell reports, 2019 - Elsevier … a generated zebrafish model lead to reduced Wnt signaling. …

” [HTML] Challenges of mitochondrial DNA editing in mammalian cells: focus on treatment of cardiovascular disease VA Khotina, M Bagheri Ekta, MS Baig, WK Wu… - Vessel Plus, 2022 Atherosclerosis is the major cause of occurrence and developm…

” [HTML] Total and reduced/oxidized forms of coenzyme Q10 in fibroblasts of patients with mitochondrial disease C Watanabe, H Osaka, M Watanabe, A Miyauchi… - Molecular Genetics and …, 2023 … We studied fibroblasts from 24 patients with mi…

” Role of ferroptosis in neurological diseases MY Yao, T Liu, L Zhang, MJ Wang, Y Yang, J Gao - Neuroscience Letters, 2021 - Elsevier … syndromes with associated epilepsy, which supports the continued clinical evaluation ofEPI-743 as a the…

” Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway S Wei, T Qiu, X Yao, N Wang, L Jiang, X Jia… - Journal of hazardous …, 2020 - Elsevier … of ferroptosis on pancreatic dysfunction tr…

” Mitochondrial regulation of ferroptosis B Gan - Journal of Cell Biology, 2021 - rupress.org … processes in mitochondria that actively drive ferroptosis, discuss recently discoveredmitochondria-… Therefore, this study proposes that mitoch…

” [HTML] The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia P La Rosa, S Petrillo, R Turchi, F Berardinelli… - Redox biology, 2021 - Elsevier … As additional indicators of ferroptosis, we further analysed the FRDA mitochondrial…

” Ferroptosis is regulated by mitochondria in neurodegenerative diseases J Zhou, Y Jin, Y Lei, T Liu, Z Wan, H Meng… - … Diseases, 2020 - karger.com … in neurodegenerative diseases. Key Messages: … of ferroptosis, we conclude that mitochon…

Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death AM Battaglia, R Chirillo, I Aversa, A Sacco, F Costanzo… - Cells, 2020 - mdpi.com … This strongly suggests that ferroptosis may act as an adaptive response to … mitocho…

" Mitochondria regulation in ferroptosis H Wang, C Liu, Y Zhao, G Gao - European journal of cell biology, 2020 - Elsevier … some oxidative stress diseases, including neurodegenerative … , the pertinence betweenmitochondria and ferroptosis …

" [HTML] OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy S Ahola, PR Mejías, S Hermans, S Chandragiri… - Cell Metabolism, 2022 - Elsevier … the heart, ultimately culminating in ferropto…

" [HTML] Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy AH Kahn-Kirby, A Amagata, CI Maeder, JJ Mei… - PLoS …, 2019 - journals.plos.org … that ferroptosis contributes to the …

" Mitochondrial disease genetics update: recent insights into the molecular diagnosis and expanding phenotype of primary mitochondrial disease EM McCormick, Z Zolkipli-Cunningham… - Current Opinion in …, 2018 - journals.lww.com … technolog…

" Therapeutic in vivo delivery of gene editing agents A Raguram, S Banskota, DR Liu - Cell, 2022 - Elsevier … Editing of mitochondrial DNA is challenged by the lack of efficient methods to deliver guideRNAs into mitochondria, precluding th…

" Mitochondrial base editor induces substantial nuclear off-target mutations Z Lei, H Meng, L Liu, H Zhao, X Rao, Y Yan, H Wu… - Nature, 2022 - nature.com … Mutations in mitochondrial DNA (mtDNA) are known to be associated with most adult-…

" Curing cytoplasmic male sterility via TALEN-mediated mitochondrial genome editing T Kazama, M Okuno, Y Watari, S Yanase, C Koizuka… - Nature plants, 2019 - nature.com … to cure mitochondrial diseases 7,8 . In these studies, disease-causi…

" CRISPR-Cas9 system: A new-fangled dawn in gene editing D Gupta, O Bhattacharjee, D Mandal, MK Sen, D Dey… - Life sciences, 2019 - Elsevier … an N terminal Mitochondrial targeting sequence (MTS) to direct its transport to the mitochondria…